Police said they were called to the spot near Kearney Cinema 8 around 6:30 p.m.
Officials believe the 53-year-old driver, and only person in the car, had a medical episode, hit the pedestrian and ended up in the creek.
They said the driver was likely headed to the movies when this happened.
The pedestrian was taken to Good Samaritan Hospital where the person was treated and released.
The incident is still being investigated.